Effect of CPAP, Weight Loss, or CPAP Plus Weight Loss on Central Hemodynamics and Arterial Stiffness
نویسندگان
چکیده
منابع مشابه
CPAP, weight loss, or both for obstructive sleep apnea.
BACKGROUND Obesity and obstructive sleep apnea tend to coexist and are associated with inflammation, insulin resistance, dyslipidemia, and high blood pressure, but their causal relation to these abnormalities is unclear. METHODS We randomly assigned 181 patients with obesity, moderate-to-severe obstructive sleep apnea, and serum levels of C-reactive protein (CRP) greater than 1.0 mg per liter...
متن کاملEffect of weight loss and nutritional intervention on arterial stiffness in type 2 diabetes.
OBJECTIVE There is increased stiffness of the large central arteries in type 2 diabetic patients, and obesity is a risk factor. However, the effect of intentional weight loss on arterial stiffness is uncertain, and the purpose of the current study was to assess this effect. RESEARCH DESIGN AND METHODS Arterial stiffness was assessed by measuring aortic pulse wave velocity (aPWV) at baseline a...
متن کاملNasal CPAP and weight loss in hypertensive patients with obstructive sleep apnoea.
BACKGROUND The high prevalence of obstructive sleep apnoea (OSA) in patients with systemic hypertension and of hypertension in patients with OSA suggests a causal link between the two disorders. This study was carried out to determine whether nasal continuous positive airway pressure (CPAP) and weight loss affect daytime hypertension in OSA. METHODS Sixty hypertensive patients with OSA took p...
متن کاملThe effect of acute maximal exercise on postexercise hemodynamics and central arterial stiffness in obese and normal‐weight individuals
Central arterial stiffness is associated with incident hypertension and negative cardiovascular outcomes. Obese individuals have higher central blood pressure (BP) and central arterial stiffness than their normal-weight counterparts, but it is unclear whether obesity also affects hemodynamics and central arterial stiffness after maximal exercise. We evaluated central hemodynamics and arterial s...
متن کاملEffects of weight loss and insulin reduction on arterial stiffness in the SAVE trial
BACKGROUND Chronic arterial stiffness contributes to the negative health effects of obesity and insulin resistance, which include hypertension, stroke, and increased cardiovascular and all-cause mortality. Weight loss and improved insulin sensitivity are individually associated with improved central arterial stiffness; however, their combined effects on arterial stiffness are poorly understood....
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ژورنال
عنوان ژورنال: Hypertension
سال: 2017
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.117.09392